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Shree Consulting Services
Shree Consulting Services
  • About Shree Consulting Services

    Where physiology, engineering, and translational
    ​insight come together.

    At Shree Consulting Services, we help research and innovation teams navigate complex cardiovascular, microvascular, and lymphatic physiology with clarity. We blend mechanistic expertise, systems thinking, and human-centered guidance to strengthen scientific decision-making, reduce uncertainty, and support impactful discovery and development.

Our Vision

We envision a world where biomedical innovation is grounded in clarity, driven by mechanism, and aligned with human health. 

We believe interdisciplinary thinking—integrating physiology, engineering, and systems modeling—enables teams to innovate more effectively and responsibly.

Our Mission

Our mission is to help researchers, clinicians, and innovators translate complex physiology into rigorous science, thoughtful strategy, and credible communication. 

We partner with teams to design better studies, interpret biological responses with confidence, and build pathways that connect mechanisms to meaningful translational relevance.

What We Believe

Good science begins with clear mechanisms. 
Decades of work across cardiovascular, microvascular, and lymphatic systems have taught us that:

Biology is interconnected and nonlinear.
Fluid balance and tissue mechanics shape many physiological responses.
Small assumptions can create large downstream errors.
Mechanistic clarity strengthens both research and innovation.

We bring this perspective to every project—helping teams avoid common pitfalls, sharpen their rationale, and ask the questions that truly matter.

Our Approach

Insight rooted in physiology. Sharpened by engineering. Guided by systems thinking.

Mechanistic Depth

We work in areas where physiology is complex, counterintuitive, and often underappreciated, including:

Interstitial fluid balance
Edema formation and resolution
Lymphatic function and adaptation
Microvascular permeability
Organ-level fluid mechanics

This depth helps teams clarify mechanisms, interpret unexpected results, and design studies aligned with the biology that actually matters.

Quantitative & Systems-Oriented Thinking

Biological systems rarely behave in linear or isolated ways. We use modeling and systems frameworks to:

Explore interactions not obvious from experiments alone
Predict responses under different disease conditions and interventions
Stress-test assumptions and conceptual models
Support strategic planning and risk awareness

This lens helps teams anticipate failure modes, understand where complexity is hiding, and make decisions rooted in mechanism rather than intuition alone.

Translational Focus

We consistently ask: “How will this matter when the work moves beyond the bench?” Our guidance supports:

Device feasibility and physiology alignment
Mechanistic pathway development
Endpoint and model selection
Translational study design
High-impact grants and manuscripts

We help teams connect foundational physiology to clinical relevance—ensuring progress is scientifically sound and strategically meaningful.

Our Story

Shree Consulting Services grew out of more than two decades of interdisciplinary research focused on how fluids move through tissues, how lymphatic vessels behave under load, how microvascular forces shape organ responses, and how these systems adapt—or fail—under stress. 

This journey spans cardiovascular physiology, lymphatic biology, tissue biomechanics, mechanistic modeling, mentorship, translational device work, and scientific communication. 

Across these domains, one theme remained constant: 
Mechanistic clarity is the foundation of meaningful progress.
 Shree Consulting Services was founded to bring this clarity to research and innovation teams—providing insight, judgment, and support to advance rigorous, translational science.

What Sets Us Apart

A uniquely deep, interdisciplinary perspective.

Every engagement is shaped around your scientific vision, goals, and challenges.

Rare expertise in lymphatic physiology & fluid balance

A domain few consultants specialize in—yet central to edema, inflammation, and organ-level responses.

Engineering-based systems thinking

We bring structure, modeling, and first-principles reasoning to questions where biology and mechanics intersect.

Cross-disciplinary translational experience

From microvascular research to device feasibility and modeling, we work across scientific and engineering boundaries.

Scientific judgment grounded in experience

Clients don’t just receive analysis—they receive interpretation, perspective, and guidance on what matters most.

About the Founder

Ranjeet M. Dongaonkar, PhD

Founder & Principal Consultant 

Physiologist | Engineer | Systems Modeler

Dr. Ranjeet M. Dongaonkar is an expert in cardiovascular and lymphatic physiology with more than twenty years of contributions spanning:

Interstitial Fluid Balance & Tissue Biomechanics  
Edema Physiology & Organ-Specific Edema
Lymphatic System Function & Adaptation
Microvascular Permeability & Filtration
Mechanistic and first-principles modeling
Translational Device & Therapeutic Development

His work has shaped scientific understanding of edema, microvascular–lymphatic coupling, and tissue fluid behavior across multiple organ systems. He has led mechanistic investigations, built research programs, mentored scientific teams, and developed interdisciplinary collaborations across academic, clinical, and translational environments.

Shree Consulting Services was founded to bring this blend of expertise, judgment, and mentorship to teams working on complex physiological challenges.

Our Values

What guides our work.

Scientific Rigor with Purpose

Clear mechanisms, meaningful questions, and thoughtful interpretation.

Multidisciplinary Perspective

Integrating systems thinking with physiology and engineering to illuminate complexity.

Impact Through Translation

Connecting mechanism to real-world applications and human health.

Collaboration & Partnership

We work with teams as allies, not just advisors.

Integrity & Accountability

Honest communication and dependable support throughout every project.

Mentorship & Growth

A commitment to strengthening scientific thinking at every level.

Let’s Explore Your Scientific Questions Together

Whether you’re designing a pivotal study, developing a biomedical device, interpreting complex data, or refining your scientific narrative, we’d be glad to help.